Since the high speed train line has been opened, Reims is linked not only to Paris, but also to major cities in the country: Lille, Bordeaux, Nantes, Strasbourg, ... Charles De Gaulle airport is only 30 minutes away and offers good connections to the South-East Lyon, Avignon, Marseille, Nice, Montpellier. Trains to cities other than Paris leave from the brand new Champagne-Ardenne TGV station, located just outside the city. This station is connected to the central station through bus and local train. When booking your ticket, check the station you'll be arriving to or leaving from as many people get mixed up and miss their train
Although one can get cheaper tickets if travelling on the regular train lines with a change of trains in Ãpernay, it will take over 2 hours and one might get a much better deal buying a TGV ticket a few weeks in advance.